Theiler's disease is a viral [[hepatitis]] that affects [[horse]]s.
== History ==
It was described in 1919 by [[Arnold Theiler]], a [[South Africa]]n [[veterinary surgeon]].
== Aetiology ==
This condition appears to be due to a [[pegivirus]].ref== Epidemiology ==
This condition most commonly occurs after the administration of a horse origin biological agent such as serum or tetanus antitoxin. It appears to be spreadable within a premises. Cases may be subclinical. In the Northern hemisphere it is most common between August to November.
== Clinical ==
The usual presentation is of [[Anorexia (symptom)|]], icterus (dark [[urine]], pale , yellowing of [[cornea]]s), fever (~50%), weight loss (uncommon), ventral [[oedema]], jugular pulses, [[ileus]] and acute respiratory distress. Features of [[hepatic encephalopathy]] may be present (aggression, [[lethargy]], maniacal behavior, central [[blindness]] and [[ataxia]]).